Richard Carrier has authored a fascinating post on the origin of life and statistics.
Also, Robert Hazen wrote something ideal for this discussion.
My Book has a very lengthy discussion on these issues, exposing the fallacies of creationist calculations about the origin of life. Even if it was an improbable event, conservative estimates (which I cite in my book) show that over a million life-friendly planets exist in the universe, and of course each of these planets is freakin' huge and has hundreds of millions of years to produce one simple self-replicating system that can evolve into the first living cell.
Also, I've got some good news: The producer of the Infidel Guy show has got in touch with me, and I may make an appearance on the show. We've tentatively scheduled it for May 21st.